Neurofibromatosis was first described by von Recklinghausen in 1882 and is characterized by cafe-au-fait spots in the skin, skin lesion and tumor of the central and peripheral nervous systems with its hereditary and chronic progressive nature. (Harkins & Reed, 1969; Schonebeck Lju ngberg, 1970). This disease is occasionally associated with anomalies of skeletal system or other organs, visceral lesions or mental defect (Aegerter, 1950; Rosman & Pearce, 1957).
Gastric neurofibromatosis. associated with von Recklinghausen´s disease has been rarely reported as well as those of small and large intestine, gall bladder, tongue and pharynx. The majority of gastro-intestinal neurofibromatosis occurs in the small and large intestine and the stomach lesion_ is rarer.
Gastrointestinal neurofibromatosis frequently has its first clinical manifestation as gastrointestinal bleeding and perforation in the severe case (Farrar & Chappell, 1959; Wilkerson, 1971).
A case of von Recklinghausen´s disease with a gastric neurofibrozna was encountered, who had massive gastric bleeding due to ulceration of the tumor and died. The clinical course and histopathologic findings of autopsy are presented.
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